IL-4RA and IL-13 Polymorphisms and Cytokine Synthesis in Children with Alternaria Sensitive Moderate-Severe Asthma

IL-4RA and IL-13 Polymorphisms and Cytokine Synthesis in Children with Alternaria Sensitive Moderate-Severe Asthma

Methods We examined five IL-4RA (ile75val, glu400ala), cys431arg, ser503pro, gln576arg) and IL-13 arg110gln polymorphisms (SNPs) and Alternaria-stimulated cytokine synthesis in 35 Alternaria-sensitive moderate-severe asthmatic children compared to 53 Alternaria-sensitive mild and 16 non-mold-sensiti...

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Veröffentlicht in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S116-S116
Hauptverfasser: Knutsen, A.P, Kariuki, B, Vijay, H, Shah, M.R
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Asthma
Cytokines
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Zusammenfassung:Methods We examined five IL-4RA (ile75val, glu400ala), cys431arg, ser503pro, gln576arg) and IL-13 arg110gln polymorphisms (SNPs) and Alternaria-stimulated cytokine synthesis in 35 Alternaria-sensitive moderate-severe asthmatic children compared to 53 Alternaria-sensitive mild and 16 non-mold-sensitive moderate-severe asthmatic children.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.462