The Effects of Estradiol on IL-13-induced Airway Hyperresponsiveness in a Mouse Model

The Effects of Estradiol on IL-13-induced Airway Hyperresponsiveness in a Mouse Model

[...]the exact effect of estrogen on lung physiology in vivo remains poorly defined. Since IL-13 induces an asthma-like state in mice, including airway inflammation and airway hyperresponsiveness (AHR), we used this model system to study the in vivo effects of estradiol on IL-13-induced AHR.

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Veröffentlicht in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S258-S258
Hauptverfasser: Segal, M, Jia, S, Gendapodi, P, Berro, A, Casale, T.B
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Asthma
Estrogens
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Zusammenfassung:[...]the exact effect of estrogen on lung physiology in vivo remains poorly defined. Since IL-13 induces an asthma-like state in mice, including airway inflammation and airway hyperresponsiveness (AHR), we used this model system to study the in vivo effects of estradiol on IL-13-induced AHR.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.1025