Esophageal Remodeling Develops as a Consequence of Tissue Specific Interleukin (IL)-5 Induced Eosinophilia

Esophageal Remodeling Develops as a Consequence of Tissue Specific Interleukin (IL)-5 Induced Eosinophilia

Results An impressive accumulation of collagen in the epithelial mucosa and lamina propria, and basal layer thickening was observed in the esophageal biopsies from EE patients (P < 0.001) compared to normal individuals as well as in mice with experimental EE (P < 0.001).

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Veröffentlicht in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S255-S255
Hauptverfasser: Wang, M, Collins, M, Putnam, P, Rothenberg, M.E, Mishra, A
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Collagen
Medical research
Rodents
Transgenic animals
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Zusammenfassung:Results An impressive accumulation of collagen in the epithelial mucosa and lamina propria, and basal layer thickening was observed in the esophageal biopsies from EE patients (P < 0.001) compared to normal individuals as well as in mice with experimental EE (P < 0.001).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.1013