Rac2 Function in Eosinophil Superoxide Generation and Allergic Airway Inflammation

Rac2 Function in Eosinophil Superoxide Generation and Allergic Airway Inflammation

Methods Eosinophils from CD2-IL-5 transgenic mice (WT) and Rac2-/- mice bred against this background (Rac2-/-/IL-5 Tg), were compared for their ability to release superoxide in response to phorbol myristate acetate.

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Veröffentlicht in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S42-S43
Hauptverfasser: Lacy, P, Lo, A, Mitchell, T, Abel, M, Dooley, J, Vliagoftis, H, Williams, D.A, Rothenberg, M.E, Eitzen, G, Zimmermann, N
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Leukocytes
Oxygen
Rodents
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Zusammenfassung:Methods Eosinophils from CD2-IL-5 transgenic mice (WT) and Rac2-/- mice bred against this background (Rac2-/-/IL-5 Tg), were compared for their ability to release superoxide in response to phorbol myristate acetate.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.173