Tacrolimus Hydrate Ointment Inhibits Skin Plasma Extravasation Induced by Topically Applied m -Xylene But Not Capsaicin in Rat

Capsaicin (10 mM) and m-xylene (99%) were applied to the shaved abdomen of anesthetized rats at 8 h after pretreatment with tacrolimus hydrate ointment (0.01%, 0.03%, or 0.1%) or its vehicle only.

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Veröffentlicht in:Journal of allergy and clinical immunology 2007, Vol.119 (1), p.S207-S207
Hauptverfasser: Morii, S, Kondo, F, Ikai, Y, Miyake, M, Futamura, M, Ito, K, Sakamoto, T
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Sprache:eng
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Zusammenfassung:Capsaicin (10 mM) and m-xylene (99%) were applied to the shaved abdomen of anesthetized rats at 8 h after pretreatment with tacrolimus hydrate ointment (0.01%, 0.03%, or 0.1%) or its vehicle only.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2006.12.181