Effect of IL-13 and IL-13 Mutant (IL-13E13K) on Airway Hyperresponsiveness (AHR) and Airway Smooth Muscle (ASM) In Mice

Effect of IL-13 and IL-13 Mutant (IL-13E13K) on Airway Hyperresponsiveness (AHR) and Airway Smooth Muscle (ASM) In Mice

IL-13E13K blocks the effects of IL-13 to cause AHR and to inhibit Iso relaxation. [...]IL-13E13K is broncho-protective both in vivo and in vitro.

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Veröffentlicht in:Journal of allergy and clinical immunology 2007, Vol.119 (1), p.S136-S137
Hauptverfasser: Gendapodi, P.R, Kioi, M, Puri, R.K, Abel, P, Townley, R.G
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Muscular system
Rodents
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Zusammenfassung:IL-13E13K blocks the effects of IL-13 to cause AHR and to inhibit Iso relaxation. [...]IL-13E13K is broncho-protective both in vivo and in vitro.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2006.11.663