Anti-C1q-autoantibodies in SLE patients
Patients having autoimmune chronic diseases may develop anti-C1q- autoantibodies. Anti-C1q-autoantibodies were determined in sera from 42 SLE-patients treated at the Belarus Rheumatology Center. All diagnoses were confirmed according to American Rheumatology Association criteria. The majority of pat...
Gespeichert in:
| Veröffentlicht in: | Journal of allergy and clinical immunology 2004-02, Vol.113 (2), p.S132-S132 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | S132 |
|---|---|
| container_issue | 2 |
| container_start_page | S132 |
| container_title | Journal of allergy and clinical immunology |
| container_volume | 113 |
| creator | Perahud, I.A. Titova, I.P. Hidchenko, S.V. Schifferli, J.A. Sadallah, S. Titov, L.P. DuBuske, L.M. |
| description | Patients having autoimmune chronic diseases may develop anti-C1q- autoantibodies.
Anti-C1q-autoantibodies were determined in sera from 42 SLE-patients treated at the Belarus Rheumatology Center. All diagnoses were confirmed according to American Rheumatology Association criteria. The majority of patients were female (95.2%). Clinical characteristics of patients: 4 (9%) had mild disease, 25 (60%) – moderate disease, and 13 (31%) – severe disease. The control group included 10 healthy adults. The concentration of anti-C1q- autoantibodies was determined by an ELISA method.
The level of anti-C1q- autoantibodies in SLE patients (118.16 ± 24.88 U/ml) was significantly greater (p |
| doi_str_mv | 10.1016/j.jaci.2003.12.469 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_elsev</sourceid><recordid>TN_cdi_proquest_journals_1504870564</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0091674903032846</els_id><sourcerecordid>3239825851</sourcerecordid><originalsourceid>FETCH-LOGICAL-e814-b8bbf643fd2eec796f0b935ec16802cbacad97c88c35336085bc094cee2cb5fb3</originalsourceid><addsrcrecordid>eNotkE9LxDAUxIMoWKtfwFPBg6fUl6ZJE_CylPUPFDy495Ckr5Ai7W7T-vnNsp6GYR7zhh8hjwxKBky-jOVofSgrAF6yqqylviIZA91QqSpxTTIAzahsan1L7mIcIXmudEaed9MaaMtO1G7rbJNxcx8wFmEqvrt9cbRrwGmN9-RmsD8RH_41J4e3_aH9oN3X-2e76ygqVlOnnBtkzYe-QvSNlgM4zQV6JhVU3llve914pTwXnEtQwnnQtUdMoRgcz8nTpfa4zKcN42rGeVum9NEwAbVqQKT6nLxerjAt-Q24mOjTSo99WNCvpp-DYWDOZMxozmTMmYxhlUlk-B-RrFdo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1504870564</pqid></control><display><type>article</type><title>Anti-C1q-autoantibodies in SLE patients</title><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Perahud, I.A. ; Titova, I.P. ; Hidchenko, S.V. ; Schifferli, J.A. ; Sadallah, S. ; Titov, L.P. ; DuBuske, L.M.</creator><creatorcontrib>Perahud, I.A. ; Titova, I.P. ; Hidchenko, S.V. ; Schifferli, J.A. ; Sadallah, S. ; Titov, L.P. ; DuBuske, L.M.</creatorcontrib><description>Patients having autoimmune chronic diseases may develop anti-C1q- autoantibodies.
Anti-C1q-autoantibodies were determined in sera from 42 SLE-patients treated at the Belarus Rheumatology Center. All diagnoses were confirmed according to American Rheumatology Association criteria. The majority of patients were female (95.2%). Clinical characteristics of patients: 4 (9%) had mild disease, 25 (60%) – moderate disease, and 13 (31%) – severe disease. The control group included 10 healthy adults. The concentration of anti-C1q- autoantibodies was determined by an ELISA method.
The level of anti-C1q- autoantibodies in SLE patients (118.16 ± 24.88 U/ml) was significantly greater (p<0.05) than in the control group (4.9 ± 1.95 U/ml). There was a significant correlation between disease activity and serum anti-C1q- autoantibody levels. The greatest anti-C1q- autoantibody titers were found in SLE patients with severe disease (215.67 ± 45.42 U/ml), while in patients with moderate and low disease anti-C1q- autoantibody levels were 82.13 ± 30.36 U/ml and 26.5 ± 12.01 U/ml respectively. There was also positive correlation between anti-C1q- autoantibody levels and antibodies to DNA (r=0.36).
The evaluation of anti-C1q- autoantibody concentrations may assist in assessment of the disease severity of SLE patients.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2003.12.469</identifier><language>eng</language><publisher>St. Louis: Mosby, Inc</publisher><ispartof>Journal of allergy and clinical immunology, 2004-02, Vol.113 (2), p.S132-S132</ispartof><rights>2004</rights><rights>Copyright Elsevier Limited Feb 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaci.2003.12.469$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids></links><search><creatorcontrib>Perahud, I.A.</creatorcontrib><creatorcontrib>Titova, I.P.</creatorcontrib><creatorcontrib>Hidchenko, S.V.</creatorcontrib><creatorcontrib>Schifferli, J.A.</creatorcontrib><creatorcontrib>Sadallah, S.</creatorcontrib><creatorcontrib>Titov, L.P.</creatorcontrib><creatorcontrib>DuBuske, L.M.</creatorcontrib><title>Anti-C1q-autoantibodies in SLE patients</title><title>Journal of allergy and clinical immunology</title><description>Patients having autoimmune chronic diseases may develop anti-C1q- autoantibodies.
Anti-C1q-autoantibodies were determined in sera from 42 SLE-patients treated at the Belarus Rheumatology Center. All diagnoses were confirmed according to American Rheumatology Association criteria. The majority of patients were female (95.2%). Clinical characteristics of patients: 4 (9%) had mild disease, 25 (60%) – moderate disease, and 13 (31%) – severe disease. The control group included 10 healthy adults. The concentration of anti-C1q- autoantibodies was determined by an ELISA method.
The level of anti-C1q- autoantibodies in SLE patients (118.16 ± 24.88 U/ml) was significantly greater (p<0.05) than in the control group (4.9 ± 1.95 U/ml). There was a significant correlation between disease activity and serum anti-C1q- autoantibody levels. The greatest anti-C1q- autoantibody titers were found in SLE patients with severe disease (215.67 ± 45.42 U/ml), while in patients with moderate and low disease anti-C1q- autoantibody levels were 82.13 ± 30.36 U/ml and 26.5 ± 12.01 U/ml respectively. There was also positive correlation between anti-C1q- autoantibody levels and antibodies to DNA (r=0.36).
The evaluation of anti-C1q- autoantibody concentrations may assist in assessment of the disease severity of SLE patients.</description><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNotkE9LxDAUxIMoWKtfwFPBg6fUl6ZJE_CylPUPFDy495Ckr5Ai7W7T-vnNsp6GYR7zhh8hjwxKBky-jOVofSgrAF6yqqylviIZA91QqSpxTTIAzahsan1L7mIcIXmudEaed9MaaMtO1G7rbJNxcx8wFmEqvrt9cbRrwGmN9-RmsD8RH_41J4e3_aH9oN3X-2e76ygqVlOnnBtkzYe-QvSNlgM4zQV6JhVU3llve914pTwXnEtQwnnQtUdMoRgcz8nTpfa4zKcN42rGeVum9NEwAbVqQKT6nLxerjAt-Q24mOjTSo99WNCvpp-DYWDOZMxozmTMmYxhlUlk-B-RrFdo</recordid><startdate>20040201</startdate><enddate>20040201</enddate><creator>Perahud, I.A.</creator><creator>Titova, I.P.</creator><creator>Hidchenko, S.V.</creator><creator>Schifferli, J.A.</creator><creator>Sadallah, S.</creator><creator>Titov, L.P.</creator><creator>DuBuske, L.M.</creator><general>Mosby, Inc</general><general>Elsevier Limited</general><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20040201</creationdate><title>Anti-C1q-autoantibodies in SLE patients</title><author>Perahud, I.A. ; Titova, I.P. ; Hidchenko, S.V. ; Schifferli, J.A. ; Sadallah, S. ; Titov, L.P. ; DuBuske, L.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e814-b8bbf643fd2eec796f0b935ec16802cbacad97c88c35336085bc094cee2cb5fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perahud, I.A.</creatorcontrib><creatorcontrib>Titova, I.P.</creatorcontrib><creatorcontrib>Hidchenko, S.V.</creatorcontrib><creatorcontrib>Schifferli, J.A.</creatorcontrib><creatorcontrib>Sadallah, S.</creatorcontrib><creatorcontrib>Titov, L.P.</creatorcontrib><creatorcontrib>DuBuske, L.M.</creatorcontrib><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perahud, I.A.</au><au>Titova, I.P.</au><au>Hidchenko, S.V.</au><au>Schifferli, J.A.</au><au>Sadallah, S.</au><au>Titov, L.P.</au><au>DuBuske, L.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-C1q-autoantibodies in SLE patients</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><date>2004-02-01</date><risdate>2004</risdate><volume>113</volume><issue>2</issue><spage>S132</spage><epage>S132</epage><pages>S132-S132</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>Patients having autoimmune chronic diseases may develop anti-C1q- autoantibodies.
Anti-C1q-autoantibodies were determined in sera from 42 SLE-patients treated at the Belarus Rheumatology Center. All diagnoses were confirmed according to American Rheumatology Association criteria. The majority of patients were female (95.2%). Clinical characteristics of patients: 4 (9%) had mild disease, 25 (60%) – moderate disease, and 13 (31%) – severe disease. The control group included 10 healthy adults. The concentration of anti-C1q- autoantibodies was determined by an ELISA method.
The level of anti-C1q- autoantibodies in SLE patients (118.16 ± 24.88 U/ml) was significantly greater (p<0.05) than in the control group (4.9 ± 1.95 U/ml). There was a significant correlation between disease activity and serum anti-C1q- autoantibody levels. The greatest anti-C1q- autoantibody titers were found in SLE patients with severe disease (215.67 ± 45.42 U/ml), while in patients with moderate and low disease anti-C1q- autoantibody levels were 82.13 ± 30.36 U/ml and 26.5 ± 12.01 U/ml respectively. There was also positive correlation between anti-C1q- autoantibody levels and antibodies to DNA (r=0.36).
The evaluation of anti-C1q- autoantibody concentrations may assist in assessment of the disease severity of SLE patients.</abstract><cop>St. Louis</cop><pub>Mosby, Inc</pub><doi>10.1016/j.jaci.2003.12.469</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0091-6749 |
| ispartof | Journal of allergy and clinical immunology, 2004-02, Vol.113 (2), p.S132-S132 |
| issn | 0091-6749 1097-6825 |
| language | eng |
| recordid | cdi_proquest_journals_1504870564 |
| source | Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| title | Anti-C1q-autoantibodies in SLE patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T04%3A39%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_elsev&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anti-C1q-autoantibodies%20in%20SLE%20patients&rft.jtitle=Journal%20of%20allergy%20and%20clinical%20immunology&rft.au=Perahud,%20I.A.&rft.date=2004-02-01&rft.volume=113&rft.issue=2&rft.spage=S132&rft.epage=S132&rft.pages=S132-S132&rft.issn=0091-6749&rft.eissn=1097-6825&rft_id=info:doi/10.1016/j.jaci.2003.12.469&rft_dat=%3Cproquest_elsev%3E3239825851%3C/proquest_elsev%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1504870564&rft_id=info:pmid/&rft_els_id=S0091674903032846&rfr_iscdi=true |