Time-course of serum IgG4 levels and IgG inhibitory activity following withdrawal of grass pollen immunotherapy (IT)

Withdrawal of successful immunotherapy resulted in a reduction in allergen-specific IgG4 within 6 months whereas symptomatic improvement and serum inhibitory activity for allergen-IgE binding to B cells remained high for at least 2 years.

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Veröffentlicht in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S265-S265
Hauptverfasser: Wilcock, L.K., Wachholz, P.A., Na, D.H., Klunker, S., Francis, J.N., Larsen, J.N., Durham, S.R.
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Sprache:eng
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Zusammenfassung:Withdrawal of successful immunotherapy resulted in a reduction in allergen-specific IgG4 within 6 months whereas symptomatic improvement and serum inhibitory activity for allergen-IgE binding to B cells remained high for at least 2 years.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.1068