Increased non-canonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes

Increased non-canonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes

Isoform specific regions that resulted from alternative splicing were studied for their potential to be epitopes for antibodies or T cell receptors.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S59-S59
Hauptverfasser: Ng, B., Yang, F., Huston, D.P., Yan, Y., Yang, Y., Xiong, Z., Peterson, L.E., Wang, H., Yang, X.
Format: Artikel
Sprache:eng
Schlagworte:
Autoimmune diseases
Eukaryotes
Genomes
Hypotheses
Proteins
T cell receptors
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Beschreibung
Zusammenfassung:Isoform specific regions that resulted from alternative splicing were studied for their potential to be epitopes for antibodies or T cell receptors.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.251