Effects of antihistamines on human erythrocyte plasma membrane integrity and phosphatidylserine distribution In Vitro

Effects of antihistamines on human erythrocyte plasma membrane integrity and phosphatidylserine distribution In Vitro

Ca2+- ion and ionophore (A23187) addition to NEM-treated erythrocytes (positive control) yielded a small population of permeabilized cells with changed particle size, in addition to an intact cell population that exhibited FITC-annexin V binding due to PS translocation to the outer membrane.

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Veröffentlicht in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S129-S129
Hauptverfasser: Graff, G., Yanni, J.M., Momsen, M.M., Schmid, P.C., Brockman, H.L.
Format: Artikel
Sprache:eng
Schlagworte:
Asymmetry
Bacteriology
Erythrocytes
Particle size
Plasma
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Zusammenfassung:Ca2+- ion and ionophore (A23187) addition to NEM-treated erythrocytes (positive control) yielded a small population of permeabilized cells with changed particle size, in addition to an intact cell population that exhibited FITC-annexin V binding due to PS translocation to the outer membrane.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.529