Cigarette Smoke Impairs Epithelial cell Antiviral Response, Arrests Cell Cycle, and Increases Telomerase Expression

Primary cultures of bronchial epithelial cells were exposed to cigarette smoke extract (CSE-5%) and rhinovirus (RV)16 (MOI = 2). qPCR was used to quantify interferon type I & III response, viral load, telomerase expression (hTERT gene).

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Veröffentlicht in:Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S149-S149
Hauptverfasser: Fiuk, J, Tang, M, Shen, J, Quraishi, J, Avila, P.C, Favoreto, S
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Sprache:eng
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Zusammenfassung:Primary cultures of bronchial epithelial cells were exposed to cigarette smoke extract (CSE-5%) and rhinovirus (RV)16 (MOI = 2). qPCR was used to quantify interferon type I & III response, viral load, telomerase expression (hTERT gene).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.556