Induction of Specific Th1 Responses and Suppression of IgE Antibody Formation and Airway Eosinophilia by Vaccination with Plasmid DNA Encoding Bla g 1

Induction of Specific Th1 Responses and Suppression of IgE Antibody Formation and Airway Eosinophilia by Vaccination with Plasmid DNA Encoding Bla g 1

[...]the polarity of the immune response upon in vitro restimulation with rBla g 1 is changed in Bla g 1-vaccinated mice, with a resulting decrease in Th2 cytokines IL-4 and IL-5 and an increase in the immunoregulatory cytokine IL-10.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S146-S146
Hauptverfasser: Yoo, T.J, Zhou, Y, Ensell, M, Glickstein, J, Kermany, M.H, Cai, Q, Cai, C, Kim, J, Kim, P, Liu, W, Zhou, B
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Cytokines
Deoxyribonucleic acid
DNA
Rodents
Vaccines
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Zusammenfassung:[...]the polarity of the immune response upon in vitro restimulation with rBla g 1 is changed in Bla g 1-vaccinated mice, with a resulting decrease in Th2 cytokines IL-4 and IL-5 and an increase in the immunoregulatory cytokine IL-10.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.547