Regulatory T-cell Patterns and Cytokine Profiles Suggest the Development of Tolerance in Patients Undergoing Peanut Oral Immunotherapy (OIT)

Regulatory T-cell Patterns and Cytokine Profiles Suggest the Development of Tolerance in Patients Undergoing Peanut Oral Immunotherapy (OIT)

Peripheral blood mononuclear cells (PBMCs) were isolated from 21 patients (1 to 16 years-old) enrolled in an open peanut OIT trial and stimulated in the presence of crude peanut extract, Ara h 2, and Concanavalin A (ConA) every six months for two years.

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Veröffentlicht in:Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S151-S151
Hauptverfasser: Bird, J.A, Scurlock, A.M, Perry, T.T, Jones, S.M, Pons, L.A, Kulis, M.D, Burks, A.W
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Cell culture
Cytokines
Medical research
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Zusammenfassung:Peripheral blood mononuclear cells (PBMCs) were isolated from 21 patients (1 to 16 years-old) enrolled in an open peanut OIT trial and stimulated in the presence of crude peanut extract, Ara h 2, and Concanavalin A (ConA) every six months for two years.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.564