The Role of BTK in TLR Signaling
While the literature has pointed to the importance of Btk in TLR induced inflammation and XLA patient cells have demonstrated decreased inflammatory response when stimulated with TLR ligands, this novel neutrophil assay for defects in TLR signaling is not useful in assessing possible TLR dysfunction...
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| Veröffentlicht in: | Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S92-S92 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | While the literature has pointed to the importance of Btk in TLR induced inflammation and XLA patient cells have demonstrated decreased inflammatory response when stimulated with TLR ligands, this novel neutrophil assay for defects in TLR signaling is not useful in assessing possible TLR dysfunction due to Btk deficiency. |
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| ISSN: | 0091-6749 1097-6825 |
| DOI: | 10.1016/j.jaci.2008.12.329 |