ChemInform Abstract: Palladium-Catalyzed Intramolecular Cyclization of 2-Iodobenzamides: An Efficient Synthesis of 3-Acyl Isoindolin-1-ones and 3-Hydroxy-3-acylisoindolin-1-ones

An efficient Pd‐catalyzed cyclization of ortho‐iodobenzamides (I) is developed to give 3‐acylated isoindolin‐2‐ones (II) in moderate to good yields.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2014-02, Vol.45 (5), p.no-no
Hauptverfasser:	Chen, Wanli, Jin, Lina, Zhu, Yinghong, Cao, Xiaoji, Zheng, Lebin, Mo, Weimin
Format:	Artikel
Sprache:	eng
Schlagworte:	catalysis catalysis, phase‐transfer catalysis indole derivatives indole derivatives, isoindole derivatives isoindole derivatives phase-transfer catalysis ring closure reactions
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	An efficient Pd‐catalyzed cyclization of ortho‐iodobenzamides (I) is developed to give 3‐acylated isoindolin‐2‐ones (II) in moderate to good yields.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201405115