Chronic binge alcohol (CBA) consumption increases cell death and alters myogenic gene expression in skeletal muscle satellite cells

Chronic binge alcohol (CBA) consumption increases cell death and alters myogenic gene expression in skeletal muscle satellite cells

[...]a significant increase in SC Smad 2 gene expression, the downstream signaling intermediate of TGF-?1 signaling, was observed during proliferation; suggesting a role for this pathway in inhibiting myogenesis.

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Bibliographische Detailangaben
Veröffentlicht in:Alcohol (Fayetteville, N.Y.) N.Y.), 2013-11, Vol.47 (7), p.575-575
Hauptverfasser: Simon, L, LeCapitaine, N, Berner, P, Dodd, T, Vande Stouwe, C, Molina, P
Format: Artikel
Sprache:eng
Schlagworte:
Alcohol
Consumption
Gene expression
Muscular system
Musculoskeletal system
Psychiatry
Satellites
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:[...]a significant increase in SC Smad 2 gene expression, the downstream signaling intermediate of TGF-?1 signaling, was observed during proliferation; suggesting a role for this pathway in inhibiting myogenesis.
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2013.09.034