Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies

Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies

Results Statistical analyses, hierarchical and k-means clustering, principal component analysis, and dynamic network analysis suggested monocyte chemotactic protein-1 / chemokine (C-C motif) ligand 2 (MCP-1/CCL2) and IL-1 as central coordinators of hepatocyte-mediated inflammation in C57BL/6 mouse h...

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Veröffentlicht in:Journal of critical care 2013-12, Vol.28 (6), p.e28-e28
Hauptverfasser: Zamora, Ruben, Ziraldo, Cordelia, Namas, Rami, Almahmoud, Khalid, Tapias, Victor, Mi, Qi, Barclay, Derek, Jefferson, Bahiyyah, Chen, Guoqiang, Billiar, Timothy, Vodovotz, Yoram
Format: Artikel
Sprache:eng
Schlagworte:
Critical Care
Hypoxia
Principal components analysis
Rodents
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Zusammenfassung:Results Statistical analyses, hierarchical and k-means clustering, principal component analysis, and dynamic network analysis suggested monocyte chemotactic protein-1 / chemokine (C-C motif) ligand 2 (MCP-1/CCL2) and IL-1 as central coordinators of hepatocyte-mediated inflammation in C57BL/6 mouse hepatocytes.
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2013.07.005