Arrangement of Magnets for a Magnetically Targeted Drug Delivery System — Guide Efficiency of Ferromagnetic Particles

We have been developing a magnetically targeted drug delivery system (MT-DDS), which involves a drug having small biocompatible magnetic particles and a high-gradient magnetic field to guide it in the targeted region. Efficient drug navigation requires that the drug be prevented from accumulating on...

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Veröffentlicht in:TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan) 2006, Vol.41(8), pp.365-370
Hauptverfasser: MISHIMA, Fumihito, FUJIMOTO, Suketaka, TAKEDA, Shin-ichi, IZUMI, Yoshinobu, NISHIJIMA, Shigehiro
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Sprache:eng ; jpn
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Zusammenfassung:We have been developing a magnetically targeted drug delivery system (MT-DDS), which involves a drug having small biocompatible magnetic particles and a high-gradient magnetic field to guide it in the targeted region. Efficient drug navigation requires that the drug be prevented from accumulating on the wall of the blood vessel when in route to the targeted region, thus an appropriate magnetic field must be designed. Magnet arrangement was studied to obtain an efficient drug delivery system by calculating the trajectory of the ferromagnetic particles in the blood vessel.
ISSN:0389-2441
1880-0408
DOI:10.2221/jcsj.41.365