Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon

We have developed a highly chemoselective hydrogenation method using a novel palladium catalyst supported on spherical carbon (0.5 % Pd/SC). The 0.5 % Pd/SC exhibited a novel catalytic activity and could achieve the chemoselective hydrogenation of alkynes, alkenes, azides, nitro groups, and aliphatic O‐tert‐butyldimethylsilyl (TBS) ethers without hydrogenolysis of benzyl esters, benzyl ethers, nitriles, aromatic ketones, N‐carbobenzyloxy (N‐Cbz) protective groups, and aromatic O‐TBS ethers. Highly selective spheres: The chemoselective hydrogenation of CC multiple bonds, azides, nitro groups, and aliphatic O‐tert‐butyldimethylsilyl (TBS) ethers is achieved in the presence of benzyl esters, benzyl ethers, nitriles, aromatic ketones, N‐carbobenzyloxy (Cbz) protective groups, and aromatic O‐TBS ethers by a novel heterogeneous palladium catalyst supported on spherical carbon (0.5 % Pd/SC).