A Cycloalkane-based Thermomorphic System for Organocatalytic Cyclopropanation Using Ammonium Ylides
Highly polar ammonium ylide intermediates derived from α-halocarbonyl compounds were successfully trapped by cycloalkane phase-tagged activated alkenes via a cycloalkane-based thermomorphic (CBT) process, which allows for facile product isolation using a single liquid–liquid extraction step to effec...
Gespeichert in:
| Veröffentlicht in: | Chemistry letters 2011-10, Vol.40 (10), p.1077-1078 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Highly polar ammonium ylide intermediates derived from α-halocarbonyl compounds were successfully trapped by cycloalkane phase-tagged activated alkenes via a cycloalkane-based thermomorphic (CBT) process, which allows for facile product isolation using a single liquid–liquid extraction step to effectively generate cyclopropane libraries in the cyclohexane phase. |
|---|---|
| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.2011.1077 |