Ring Expansion Approach to Azaspiro[4.5]decane Skeletons via Electrophilic Activation of Benzocyclobutenols Bearing Pyridyl Group

Facile construction of azaspiro[4.5]decane skeletons was enabled by the ring expansion of benzocyclobutenols substituted with a pyridyl group, triggered by electrophilic activation of the heteroaromatic moiety.

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Veröffentlicht in:Chemistry letters 2011-06, Vol.40 (6), p.612-613
Hauptverfasser: Hayashi, Taiki, Ohmori, Ken, Suzuki, Keisuke
Format: Artikel
Sprache:eng
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Zusammenfassung:Facile construction of azaspiro[4.5]decane skeletons was enabled by the ring expansion of benzocyclobutenols substituted with a pyridyl group, triggered by electrophilic activation of the heteroaromatic moiety.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2011.612