Application of FITC-labeled Ternatin on Its Cellular Localization in 3T3-L1 Murine Preadipocytes

Application of FITC-labeled Ternatin on Its Cellular Localization in 3T3-L1 Murine Preadipocytes

The cellular localization of a potent fat-accumulation inhibitor (−)-ternatin was investigated. FITC-labeled ternatin, a chemical probe for current study, was synthesized from a highly bioactive ternatin analogue using Click Chemistry, which was found to be bioactive. The treatment of 3T3-L1 murine...

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Veröffentlicht in:Chemistry letters 2009-02, Vol.38 (2), p.150-151
Hauptverfasser: Shimokawa, Kenichiro, Ohno, Osamu, Yamada, Kaoru, Oba, Yuichi, Uemura, Daisuke
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container_end_page 151
container_issue 2
container_start_page 150
container_title Chemistry letters
container_volume 38
creator Shimokawa, Kenichiro
Ohno, Osamu
Yamada, Kaoru
Oba, Yuichi
Uemura, Daisuke
description The cellular localization of a potent fat-accumulation inhibitor (−)-ternatin was investigated. FITC-labeled ternatin, a chemical probe for current study, was synthesized from a highly bioactive ternatin analogue using Click Chemistry, which was found to be bioactive. The treatment of 3T3-L1 murine preadipocytes with synthetic probe revealed that (−)-ternatin is localized in a specific organelle of 3T3-L1 cells.
doi_str_mv 10.1246/cl.2009.150
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title Application of FITC-labeled Ternatin on Its Cellular Localization in 3T3-L1 Murine Preadipocytes
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