Application of FITC-labeled Ternatin on Its Cellular Localization in 3T3-L1 Murine Preadipocytes
The cellular localization of a potent fat-accumulation inhibitor (−)-ternatin was investigated. FITC-labeled ternatin, a chemical probe for current study, was synthesized from a highly bioactive ternatin analogue using Click Chemistry, which was found to be bioactive. The treatment of 3T3-L1 murine...
Gespeichert in:
| Veröffentlicht in: | Chemistry letters 2009-02, Vol.38 (2), p.150-151 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The cellular localization of a potent fat-accumulation inhibitor (−)-ternatin was investigated. FITC-labeled ternatin, a chemical probe for current study, was synthesized from a highly bioactive ternatin analogue using Click Chemistry, which was found to be bioactive. The treatment of 3T3-L1 murine preadipocytes with synthetic probe revealed that (−)-ternatin is localized in a specific organelle of 3T3-L1 cells. |
|---|---|
| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.2009.150 |