Synthesis and Transport Activities of HIV–Tat Peptide-modified Cholesterol Pullulan

Synthesis and Transport Activities of HIV–Tat Peptide-modified Cholesterol Pullulan

A complex in which the cell-penetrating peptide HIV–Tat and cholesterol pullulan were conjugated through a disulfide bond was synthesized. The complex showed marked cell penetrating activities as a vector.

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Veröffentlicht in:Chemistry letters 2009-10, Vol.38 (10), p.970-971
Hauptverfasser: Kimura, Aki, Kamo, Yosuke, Takashima, Yuuki, Kanazawa, Takanori, Okada, Hiroaki, Fukuda, Tsunehiko
Format: Artikel
Sprache:eng
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Zusammenfassung:A complex in which the cell-penetrating peptide HIV–Tat and cholesterol pullulan were conjugated through a disulfide bond was synthesized. The complex showed marked cell penetrating activities as a vector.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2009.970