Activation of Urea as a Leaving Group in Substitution Reactions of Formamidine Ureas

The reactions of formamidine ureas with amines take different paths under protic vs. nonprotic conditions; loss of the urea fragment has been observed for the first time when protons are made available intra- or intermolecularly.

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Veröffentlicht in:Chemistry letters 2005-01, Vol.34 (1), p.78-79
Hauptverfasser: Díaz, David D, Lewis, Warren G, Finn, M. G
Format: Artikel
Sprache:eng
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Zusammenfassung:The reactions of formamidine ureas with amines take different paths under protic vs. nonprotic conditions; loss of the urea fragment has been observed for the first time when protons are made available intra- or intermolecularly.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2005.78