De Novo Design of Hemoprotein Model with Peroxidase Activity toward Lipophilic Peroxide

De Novo Design of Hemoprotein Model with Peroxidase Activity toward Lipophilic Peroxide

A single-chained 49-mer-polypeptide tethering iron(III)-porphyrin folded into a certain conformation with bis-histidine coordination and consumed favorably linoleic acid hydroperoxide rather than H2O2.

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Veröffentlicht in:Chemistry letters 2000-06, Vol.29 (6), p.648-649
Hauptverfasser: Tomizaki, Kin-ya, Nishino, Hidekazu, Kato, Tamaki, Miike, Akira, Nishino, Norikazu
Format: Artikel
Sprache:eng
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Zusammenfassung:A single-chained 49-mer-polypeptide tethering iron(III)-porphyrin folded into a certain conformation with bis-histidine coordination and consumed favorably linoleic acid hydroperoxide rather than H2O2.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2000.648