Chemistry and Antimicrobial Activities of 3,5,7,9-Decatetrayn-2-ol and Related Compounds

Unstable 3,5,7,9-octatetrayn-2-ol showed potent antimicrobial activity against bacteria and fungi. Its trimethylsilyl derivative, which possessed much improved stability, showed comparable activity. It is due to desilylation under neutral aqueous conditions.

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Veröffentlicht in:Chemistry letters 1997-06, Vol.26 (6), p.535-536
Hauptverfasser: Yamaguchi, Masahiko, Park, Hyeon-Joo, Hirama, Masahiro
Format: Artikel
Sprache:eng
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Zusammenfassung:Unstable 3,5,7,9-octatetrayn-2-ol showed potent antimicrobial activity against bacteria and fungi. Its trimethylsilyl derivative, which possessed much improved stability, showed comparable activity. It is due to desilylation under neutral aqueous conditions.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1997.535