A Free Radical in Human Cerebrospinal Fluid Investigated by EPR
We have detected a free radical in human cerebrospinal fluid (CSF) and have identified as ascorbyl radical using electron paramagnetic resonance (EPR). EPR spectrum of the radical in CSF was compared with one in the corresponding serum. Determination of the ascorbyl radical concentrations in CSF and...
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| Veröffentlicht in: | Chemistry letters 1997-01, Vol.26 (6), p.551-552 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | We have detected a free radical in human cerebrospinal fluid (CSF) and have identified as ascorbyl radical using electron paramagnetic resonance (EPR). EPR spectrum of the radical in CSF was compared with one in the corresponding serum. Determination of the ascorbyl radical concentrations in CSF and serum was attempted using known concentrations of a nitroxyl radical. Moreover, an alternative method to measure the biological radical was provided. |
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| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.1997.551 |