An Unexpected Route to Fluorinated Anisoles

We found a new one-pot procedure for the synthesis of polyfluoroanisoles from polyfluoroanilines. The reaction involves aromatic nucleophilic substitution of o- or p-fluorine of benzenediazonium salt with mathoxy group followed by reductive removal of the diazonium group.

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Veröffentlicht in:Chemistry letters 1996-01, Vol.25 (1), p.23-24
Hauptverfasser: Takechi, Naoto, Fukai, Yasushi, Oka, Kazuyoshi, Huisgen, Rolf
Format: Artikel
Sprache:eng
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Zusammenfassung:We found a new one-pot procedure for the synthesis of polyfluoroanisoles from polyfluoroanilines. The reaction involves aromatic nucleophilic substitution of o- or p-fluorine of benzenediazonium salt with mathoxy group followed by reductive removal of the diazonium group.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1996.23