Stereoselective Reactions. XXXIII.1) Design and Synthesis of Chiral Bidentate Amines Having a Bulky Group on the Chiral Carbon

Stereoselective Reactions. XXXIII.1) Design and Synthesis of Chiral Bidentate Amines Having a Bulky Group on the Chiral Carbon

Based on the solution structures of chiral bidentate lithium amides ((R)-3a, b) having a phenyl group on the chiral carbon, chiral bidentate amines ((R)-5a, b-8a, b and (S)-9a, b) having a bulkier group instead of a phenyl group on the chiral carbon were designed and synthesized.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & pharmaceutical bulletin 2001, Vol.49(3), pp.330-334
Hauptverfasser: TORIYAMA, Masaharu, TOKUTAKE, Norio, KOGA, Kenji
Format: Artikel
Sprache:eng
Schlagworte:
chiral amide nitrogen
chiral amine
chiral lithium amide
enantioselective deprotonation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Based on the solution structures of chiral bidentate lithium amides ((R)-3a, b) having a phenyl group on the chiral carbon, chiral bidentate amines ((R)-5a, b-8a, b and (S)-9a, b) having a bulkier group instead of a phenyl group on the chiral carbon were designed and synthesized.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.49.330