Reaction of Six-Membered Azaaromatics with Allyltributyltin

Reaction of Six-Membered Azaaromatics with Allyltributyltin

Pyridazines were reacted with allyltributyltin in the presence of chloroformate to give 1-alkoxycarbonyl-6-allyl and 1-alkoxycarbonyl-4-allyldihydropyridazines as major and minor products, respectively. The reaction system was applied to other diazines and pyrimidine and pyrazine were shown to affor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & pharmaceutical bulletin 1994/09/15, Vol.42(9), pp.1768-1773
Hauptverfasser: ITOH, Takashi, HASEGAWA, Hiroshi, NAGATA, Kazuhiro, MATSUYA, Yuji, OKADA, Mamiko, OHSAWA, Akio
Format: Artikel
Sprache:eng
Schlagworte:
1, 2, 3-triazine
alkyl chloroformate
allytributyltin
benzodiazine
Chemistry
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
Organic chemistry
Preparations and properties
pyrazine
pyridazine
pyrimidine
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Pyridazines were reacted with allyltributyltin in the presence of chloroformate to give 1-alkoxycarbonyl-6-allyl and 1-alkoxycarbonyl-4-allyldihydropyridazines as major and minor products, respectively. The reaction system was applied to other diazines and pyrimidine and pyrazine were shown to afford diallytetrahydroadducts. Benzodiazines also gave allylation products in good yields. The reaction seems to be applicable to most six-membered azaaromatics.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.42.1768