Revised Structure and Stereochemistry of Hypothemycin

A cytotoxic 14-membered resorcylic macrolide, isolated from Coriolus versicolor (L. : FR.) QUEL., was found to be identical with hypothemycin, previously isolated from Hypomyces trichothecoides TSUBAKI. The structure of hypothemycin has been elucidated to be 1 rather than the originally proposed 2.

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1993/02/15, Vol.41(2), pp.373-375
Hauptverfasser:	AGATSUMA, Tsutomu, TAKAHASHI, Akira, KABUTO, Chizuko, NOZOE, Shigeo
Format:	Artikel
Sprache:	eng
Schlagworte:	2D-NMR Biological and medical sciences Coriolus versicolor General pharmacology Hypomyces trichothecoides hypothemycin Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments revised structure X-ray crystallographic analysis
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Beschreibung
Zusammenfassung:	A cytotoxic 14-membered resorcylic macrolide, isolated from Coriolus versicolor (L. : FR.) QUEL., was found to be identical with hypothemycin, previously isolated from Hypomyces trichothecoides TSUBAKI. The structure of hypothemycin has been elucidated to be 1 rather than the originally proposed 2.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.41.373