Inhibitors of Xanthine Oxidase from Alpinia galanga
Xanthine oxidase (XO) inhibitors were isolated from the rhizomes of Alpinia galanga (Zingiberaceae), and were identified as trans-p-coumaryl diacetate (1), trans-coniferyl diacetate (2), [1'S]-1'-acetoxychavicol acetate (3), [1'S]-1'-acetoxyeugenol acetate (4) and 4-hydroxybenzal...
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| Veröffentlicht in: | Chemical & pharmaceutical bulletin 1988/01/25, Vol.36(1), pp.244-248 |
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| container_title | Chemical & pharmaceutical bulletin |
| container_volume | 36 |
| creator | NORO, TADATAKA SEKIYA, TAKESHI ABE), MASAKO KATOH(nee ODA, YASUSHI MIYASE, TOSHIO KUROYANAGI, MASANORI UENO, AKIRA FUKUSHIMA, SEIGO |
| description | Xanthine oxidase (XO) inhibitors were isolated from the rhizomes of Alpinia galanga (Zingiberaceae), and were identified as trans-p-coumaryl diacetate (1), trans-coniferyl diacetate (2), [1'S]-1'-acetoxychavicol acetate (3), [1'S]-1'-acetoxyeugenol acetate (4) and 4-hydroxybenzaldehyde (5). The type of inhibition by either 1 or 3 with respect to xanthine as a substrate was uncompetitive. |
| doi_str_mv | 10.1248/cpb.36.244 |
| format | Article |
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The type of inhibition by either 1 or 3 with respect to xanthine as a substrate was uncompetitive.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.36.244</identifier><identifier>CODEN: CPBTAL</identifier><language>eng</language><publisher>Tokyo: The Pharmaceutical Society of Japan</publisher><subject>1'-acetoxychavicol diacetate phenylpropenol ; Biological and medical sciences ; General pharmacology ; Medical sciences ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments</subject><ispartof>Chemical and Pharmaceutical Bulletin, 1988/01/25, Vol.36(1), pp.244-248</ispartof><rights>The Pharmaceutical Society of Japan</rights><rights>1989 INIST-CNRS</rights><rights>Copyright Japan Science and Technology Agency 1988</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4644-abbcc167dc26e5e56f84be99cee1c13dbb39e2fc54984cbb081bc31805a87b213</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7171333$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>NORO, TADATAKA</creatorcontrib><creatorcontrib>SEKIYA, TAKESHI</creatorcontrib><creatorcontrib>ABE), MASAKO KATOH(nee</creatorcontrib><creatorcontrib>ODA, YASUSHI</creatorcontrib><creatorcontrib>MIYASE, TOSHIO</creatorcontrib><creatorcontrib>KUROYANAGI, MASANORI</creatorcontrib><creatorcontrib>UENO, AKIRA</creatorcontrib><creatorcontrib>FUKUSHIMA, SEIGO</creatorcontrib><title>Inhibitors of Xanthine Oxidase from Alpinia galanga</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>Xanthine oxidase (XO) inhibitors were isolated from the rhizomes of Alpinia galanga (Zingiberaceae), and were identified as trans-p-coumaryl diacetate (1), trans-coniferyl diacetate (2), [1'S]-1'-acetoxychavicol acetate (3), [1'S]-1'-acetoxyeugenol acetate (4) and 4-hydroxybenzaldehyde (5). The type of inhibition by either 1 or 3 with respect to xanthine as a substrate was uncompetitive.</description><subject>1'-acetoxychavicol diacetate phenylpropenol</subject><subject>Biological and medical sciences</subject><subject>General pharmacology</subject><subject>Medical sciences</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. 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Homeopathy. Health food</topic><topic>Pharmacology. 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Pharm. Bull.</addtitle><date>1988</date><risdate>1988</risdate><volume>36</volume><issue>1</issue><spage>244</spage><epage>248</epage><pages>244-248</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><coden>CPBTAL</coden><abstract>Xanthine oxidase (XO) inhibitors were isolated from the rhizomes of Alpinia galanga (Zingiberaceae), and were identified as trans-p-coumaryl diacetate (1), trans-coniferyl diacetate (2), [1'S]-1'-acetoxychavicol acetate (3), [1'S]-1'-acetoxyeugenol acetate (4) and 4-hydroxybenzaldehyde (5). The type of inhibition by either 1 or 3 with respect to xanthine as a substrate was uncompetitive.</abstract><cop>Tokyo</cop><pub>The Pharmaceutical Society of Japan</pub><doi>10.1248/cpb.36.244</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-2363 |
| ispartof | Chemical and Pharmaceutical Bulletin, 1988/01/25, Vol.36(1), pp.244-248 |
| issn | 0009-2363 1347-5223 |
| language | eng |
| recordid | cdi_proquest_journals_1460148447 |
| source | J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | 1'-acetoxychavicol diacetate phenylpropenol Biological and medical sciences General pharmacology Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments |
| title | Inhibitors of Xanthine Oxidase from Alpinia galanga |
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