Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils

Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils

5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & pharmaceutical bulletin 1982/01/25, Vol.30(1), pp.91-96
Hauptverfasser: OKADA, JUTARO, NAKANO, KOICHI, MIYAKE, HIROSHI, YASUFUKU, SHOJI
Format: Artikel
Sprache:eng
Schlagworte:
L-1210 cells
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 96
container_issue 1
container_start_page 91
container_title Chemical & pharmaceutical bulletin
container_volume 30
creator OKADA, JUTARO
NAKANO, KOICHI
MIYAKE, HIROSHI
YASUFUKU, SHOJI
description 5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.
doi_str_mv 10.1248/cpb.30.91
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1459941426</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3132112051</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4311-662be20d54a28b5a4ad5ba4638adca97dc1aa4e37da372b41cd7989f2e60cc3b3</originalsourceid><addsrcrecordid>eNpF0E1LAzEQBuAgCtbqwX8Q8CS4aybJfuSoVWuh4EE9h9lsalPW3ZpkK_33blnRy8xhHuaFl5BLYClwWd6abZUKlio4IhMQskgyzsUxmTDGVMJFLk7JWQgbxnjGCjEh8d2jcQ19sN7tMLqdDSldLBYpfd23cW2DDRTbms599x3XiWvXrnKx83t6Zwbt4p7iB7o2RLpMgAOjM9s0gXYrmt3QPHlwoa9CdLGPtqZjWDgnJytsgr343VPy_vT4NntOli_zxexumRgpAJI855XlrM4k8rLKUGKdVShzUWJtUBW1AURpRVGjKHglwdSFKtWK25wZIyoxJVfj363vvnobot50vW-HSA0yU0qC5PmgrkdlfBeCtyu99e4T_V4D04dS9VCqFkwrGOz9aDch4of9k-ijM409SFBZedAwDgX_xzV6bVvxA5H9gRA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1459941426</pqid></control><display><type>article</type><title>Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils</title><source>J-STAGE Free</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><creator>OKADA, JUTARO ; NAKANO, KOICHI ; MIYAKE, HIROSHI ; YASUFUKU, SHOJI</creator><creatorcontrib>OKADA, JUTARO ; NAKANO, KOICHI ; MIYAKE, HIROSHI ; YASUFUKU, SHOJI</creatorcontrib><description>5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.30.91</identifier><language>eng</language><publisher>Tokyo: The Pharmaceutical Society of Japan</publisher><subject>L-1210 cells</subject><ispartof>Chemical and Pharmaceutical Bulletin, 1982/01/25, Vol.30(1), pp.91-96</ispartof><rights>The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 1982</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4311-662be20d54a28b5a4ad5ba4638adca97dc1aa4e37da372b41cd7989f2e60cc3b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27902,27903,27904</link.rule.ids></links><search><creatorcontrib>OKADA, JUTARO</creatorcontrib><creatorcontrib>NAKANO, KOICHI</creatorcontrib><creatorcontrib>MIYAKE, HIROSHI</creatorcontrib><creatorcontrib>YASUFUKU, SHOJI</creatorcontrib><title>Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils</title><title>Chemical &amp; pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.</description><subject>L-1210 cells</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><recordid>eNpF0E1LAzEQBuAgCtbqwX8Q8CS4aybJfuSoVWuh4EE9h9lsalPW3ZpkK_33blnRy8xhHuaFl5BLYClwWd6abZUKlio4IhMQskgyzsUxmTDGVMJFLk7JWQgbxnjGCjEh8d2jcQ19sN7tMLqdDSldLBYpfd23cW2DDRTbms599x3XiWvXrnKx83t6Zwbt4p7iB7o2RLpMgAOjM9s0gXYrmt3QPHlwoa9CdLGPtqZjWDgnJytsgr343VPy_vT4NntOli_zxexumRgpAJI855XlrM4k8rLKUGKdVShzUWJtUBW1AURpRVGjKHglwdSFKtWK25wZIyoxJVfj363vvnobot50vW-HSA0yU0qC5PmgrkdlfBeCtyu99e4T_V4D04dS9VCqFkwrGOz9aDch4of9k-ijM409SFBZedAwDgX_xzV6bVvxA5H9gRA</recordid><startdate>1982</startdate><enddate>1982</enddate><creator>OKADA, JUTARO</creator><creator>NAKANO, KOICHI</creator><creator>MIYAKE, HIROSHI</creator><creator>YASUFUKU, SHOJI</creator><general>The Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>1982</creationdate><title>Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils</title><author>OKADA, JUTARO ; NAKANO, KOICHI ; MIYAKE, HIROSHI ; YASUFUKU, SHOJI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4311-662be20d54a28b5a4ad5ba4638adca97dc1aa4e37da372b41cd7989f2e60cc3b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>L-1210 cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>OKADA, JUTARO</creatorcontrib><creatorcontrib>NAKANO, KOICHI</creatorcontrib><creatorcontrib>MIYAKE, HIROSHI</creatorcontrib><creatorcontrib>YASUFUKU, SHOJI</creatorcontrib><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Chemical &amp; pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OKADA, JUTARO</au><au>NAKANO, KOICHI</au><au>MIYAKE, HIROSHI</au><au>YASUFUKU, SHOJI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils</atitle><jtitle>Chemical &amp; pharmaceutical bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>1982</date><risdate>1982</risdate><volume>30</volume><issue>1</issue><spage>91</spage><epage>96</epage><pages>91-96</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.</abstract><cop>Tokyo</cop><pub>The Pharmaceutical Society of Japan</pub><doi>10.1248/cpb.30.91</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0009-2363
ispartof Chemical and Pharmaceutical Bulletin, 1982/01/25, Vol.30(1), pp.91-96
issn 0009-2363
1347-5223
language eng
recordid cdi_proquest_journals_1459941426
source J-STAGE Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry
subjects L-1210 cells
title Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T08%3A40%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Uracil%20Derivatives.%20III.%20Syntheses%20and%20Growth-inhibitory%20Activity%20against%20L-1210%20Cells%20of%205,%206-Disubstituted%20Uracils&rft.jtitle=Chemical%20&%20pharmaceutical%20bulletin&rft.au=OKADA,%20JUTARO&rft.date=1982&rft.volume=30&rft.issue=1&rft.spage=91&rft.epage=96&rft.pages=91-96&rft.issn=0009-2363&rft.eissn=1347-5223&rft_id=info:doi/10.1248/cpb.30.91&rft_dat=%3Cproquest_cross%3E3132112051%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1459941426&rft_id=info:pmid/&rfr_iscdi=true