Synthetic Inhibitors of Enzymes involved in Peptidoglycan Biosynthesis. I. Preparation of D-Alanine Chloromethylketones

New chloromethylketone derivatives and other D-alanine-containing compounds related to the peptide moiety of the bacterial peptidoglycan were synthesized in order to search inhibitors of the peptidoglycan transpeptidase.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & pharmaceutical bulletin 1978/07/25, Vol.26(7), pp.2233-2235
Hauptverfasser: NAKAMIZO, NOBUHIRO, NAKAMURA, MASASHI
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:New chloromethylketone derivatives and other D-alanine-containing compounds related to the peptide moiety of the bacterial peptidoglycan were synthesized in order to search inhibitors of the peptidoglycan transpeptidase.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.26.2233