2-Substituted Thiazolines. III

2-Ethylthiothiazoline was reacted with N-benzoyl-α-amino acids in acetic anhydride to give I. Ia was converted into II, III, IV, and V. The oxazolone ring of Ib and Ic was opened to give XI. XIb was converted into thiazoline (XII) and XIII. These thiazolines were reduced to thiazolidine (XIV) and XV...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1975-01, Vol.23 (1), p.48
Hauptverfasser: OKUTOME, TOSHIYUKI, SAKURAI, YOJIRO, KURUMI, MASATERU, KAWAMURA, HIROYUKI, SATO, SHIGEO, YAMAGUCHI, KAZUTAKA
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Sprache:eng
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Zusammenfassung:2-Ethylthiothiazoline was reacted with N-benzoyl-α-amino acids in acetic anhydride to give I. Ia was converted into II, III, IV, and V. The oxazolone ring of Ib and Ic was opened to give XI. XIb was converted into thiazoline (XII) and XIII. These thiazolines were reduced to thiazolidine (XIV) and XV, and then converted into the respective aldehydes, XVI and XVII.
ISSN:0009-2363
1347-5223