Studies on Benzoheterocyclic Derivatives. XIII. Synthesis and Pharmacological Actions of Indoline Derivatives.(4)

Thirty one derivatives of 3-alkoxy-1[ω-(N-substituted amino)-3-phenylindolin-2-one and related compounds were synthesized for pharmacological testing. As a preliminary screening test compounds were tested for analgetic-antiphlogistic activity by anti-writhing test in mice. Acute toxicity and gross behavioral changes in mice were also determined. The majority of the compounds produced anti-writhing activity.