The Structure of 9, 14-Epoxy-8, 14-seco Steroids

The more stable compound, 9, 14α-epoxy-3-methoxy-8, 14-secoestra-1, 3, 5 (10)-trien-17-one (IVa), given by cyclization of 14α-hydroxy-3-methoxy-8, 14-secoestra-1, 3, 5 (10), 9-tetraen-17-one (II), has been assigned to a 9α, 14α-epoxy compound (9S configuration).

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1973/04/25, Vol.21(4), pp.703-706
Hauptverfasser: ASAKO, TSUNEHIKO, HIRAGA, KENTARO, MIKI, TAKUICHI
Format: Artikel
Sprache:eng
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Zusammenfassung:The more stable compound, 9, 14α-epoxy-3-methoxy-8, 14-secoestra-1, 3, 5 (10)-trien-17-one (IVa), given by cyclization of 14α-hydroxy-3-methoxy-8, 14-secoestra-1, 3, 5 (10), 9-tetraen-17-one (II), has been assigned to a 9α, 14α-epoxy compound (9S configuration).
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.21.703