Thiosteroids. XXI. Episulfide Formation from Vicinal Thiocyanatohydrins and Their Acetates

Thiosteroids. XXI. Episulfide Formation from Vicinal Thiocyanatohydrins and Their Acetates

Each epimers of 2, 3-episulfides of 5β, 25D-spirostane and 17β-hydroxy-5α-androstanes having a methyl group at C-1α, C2, or C3 were synthesized via the corresponding vicinal diaxial thiocyanatohydrins. In addition the formation of both episulfides and oxides from the vicinal diaxial thiocyanatohydri...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1969/10/25, Vol.17(10), pp.2110-2119
Hauptverfasser: KOMENO, TAICHIRO, ISHIHARA, SHOICHI, ITANI, HIKARU, IWAKURA, HIKOZO, TAKEDA, KENICHI
Format: Artikel
Sprache:eng
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Zusammenfassung:Each epimers of 2, 3-episulfides of 5β, 25D-spirostane and 17β-hydroxy-5α-androstanes having a methyl group at C-1α, C2, or C3 were synthesized via the corresponding vicinal diaxial thiocyanatohydrins. In addition the formation of both episulfides and oxides from the vicinal diaxial thiocyanatohydrin acetates was discussed on the basis of the natures of the substituents.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.17.2110