Studies on Carcinostatic Substances. XXXI. Anti-tumor Action of 1-Dialkylamino-2, 3-dichloropropanes and 2-Dialkylamino-1, 3-dichloropropanes
1-Dialkylamino-2, 3-dichloropropanes, 2-dialkylamino-1, 3-dichloropropanes, and several new derivatives of nitrogen mustard having 2-chloropropyl group were synthesized and tested on Yoshida sarcoma. Mode of alkylation and hydrolysis in vitro of the former two types of compound were also discussed.
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| Veröffentlicht in: | Chemical & pharmaceutical bulletin 1960/09/25, Vol.8(9), pp.807-814 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | 1-Dialkylamino-2, 3-dichloropropanes, 2-dialkylamino-1, 3-dichloropropanes, and several new derivatives of nitrogen mustard having 2-chloropropyl group were synthesized and tested on Yoshida sarcoma. Mode of alkylation and hydrolysis in vitro of the former two types of compound were also discussed. |
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| ISSN: | 0009-2363 1347-5223 |
| DOI: | 10.1248/cpb.8.807 |