ChemInform Abstract: In vivo Antimalarial Activity of Novel 2-Hydroxy-3-anilino-1,4-naphthoquinones Obtained by Epoxide Ring-Opening Reaction

ChemInform Abstract: In vivo Antimalarial Activity of Novel 2-Hydroxy-3-anilino-1,4-naphthoquinones Obtained by Epoxide Ring-Opening Reaction

The title compounds (III) are obtained by the underexplored epoxide‐opening reaction of 2,3‐epoxy‐1,4‐naphthoquinone using aniline derivatives as nucleophiles.

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Veröffentlicht in:ChemInform 2013-12, Vol.44 (49), p.no-no
Hauptverfasser: Dias de Rezende, Lucas Cunha, Fumagalli, Fernando, Schiavon Bortolin, Marraiana, Garcia de Oliveira, Marianne, Helder de Paula, Murilo, Ferreira de Andrade-Neto, Valter, da Silva Emery, Flavio
Format: Artikel
Sprache:eng
Schlagworte:
antimalarial activity
Medical treatment
quinones (naphthalene compounds)
ring opening reactions
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Zusammenfassung:The title compounds (III) are obtained by the underexplored epoxide‐opening reaction of 2,3‐epoxy‐1,4‐naphthoquinone using aniline derivatives as nucleophiles.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201349108