Suppressive Effect of Yamato-mana (Brassica rapa L. Oleifera Group) Constituent 3-Butenyl Glucosinolate (Gluconapin) on Postprandial Hypertriglyceridemia in Mice

We examined the bioactivity of Yamato-mana (Brassica rapa L. Oleifera Group) constituent glucosinolates and found that 3-butenyl glucosinolate (gluconapin) decreased the plasma triglyceride gain induced by corn oil administration to mice. However, phenethyl glucosinolate (gluconasturtiin) had little...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2010, Vol.74 (6), p.1286-1289
Hauptverfasser:	WASHIDA, Kazuto, MIYATA, Mitsuyoshi, KOYAMA, Tomoyuki, YAZAWA, Kazunaga, NOMOTO, Kyosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	2-propenyl glucosinolate 3-butenyl glucosinolate Absorption - drug effects Animals Biological and medical sciences Brassica rapa Brassica rapa - chemistry Fundamental and applied biological sciences. Psychology Glucosinolates - pharmacology Glucosinolates - therapeutic use Hyperglycemia - drug therapy Hyperglycemia - metabolism Mice phenethyl glucosinolate Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use postprandial hypertriglyceridemia Triglycerides - metabolism Yamato-mana (Brassica rapa L. Oleifera Group)
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Zusammenfassung:	We examined the bioactivity of Yamato-mana (Brassica rapa L. Oleifera Group) constituent glucosinolates and found that 3-butenyl glucosinolate (gluconapin) decreased the plasma triglyceride gain induced by corn oil administration to mice. However, phenethyl glucosinolate (gluconasturtiin) had little effect. 2-Propenyl glucosinolate (sinigrin) also reduced the plasma triglyceride level, which suggests that alkenyl glucosinolates might be promising agents to prevent postprandial hypertriglyceridemia.
ISSN:	0916-8451 1347-6947 1347-6947
DOI:	10.1271/bbb.100018