Inhibitory effects of guarana seed extract on passive cutaneous anaphylaxis and mast cell degranulation

Inhibitory effects of guarana seed extract on passive cutaneous anaphylaxis and mast cell degranulation

This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2009-09, Vol.73 (9), p.2110-2112
Hauptverfasser: Jippo, T.(Senri Kinran Univ., Osaka (Japan)), Kobayashi, Y, Sato, H, Hattori, A, Takeuchi, H, Sugimoto, K, Shigekawa, M
Format: Artikel
Sprache:eng
Schlagworte:
ANAPHYLACTIC REACTIONS
Animals
anti-allergic effect
Biological and medical sciences
Cell Degranulation - drug effects
Cell Line, Tumor
CELULAS FIBROSAS
Chromatography, High Pressure Liquid
degranulation
DRUGS
EXTRACTOS DE SEMILLAS
EXTRAIT DE GRAINES
Fundamental and applied biological sciences. Psychology
guarana
mast cell
MAST CELLS
Mast Cells - cytology
Mast Cells - drug effects
MASTOCYTE
MEDICAMENT
MEDICAMENTOS
passive cutaneous anaphylaxis
Passive Cutaneous Anaphylaxis - drug effects
Paullinia - embryology
PAULLINIA CUPANA
Plant Extracts - pharmacology
Rats
REACCIONES ANAFILACTICAS
REACTION ANAPHYLACTIQUE
SEED EXTRACTS
Seeds - chemistry
Spectrophotometry, Ultraviolet
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells. It had no cytotoxicity on RBL-2H3 cells. These results show that GSE is a candidate for effective therapeutic material for allergic diseases.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.90205