Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro

Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro

Antiviral activities of Agaricus blazei Murill were investigated. The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol. To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethano...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2001-07, Vol.65 (7), p.1645-1647
Hauptverfasser: Sorimachi, K. (Dokkyo Univ., Mibu, Tochigi (Japan). School of Medicine), Ikehara, Y, Maezato, G, Okubo, A, Yamazaki, S, Akimoto, K, Niwa, A
Format: Artikel
Sprache:eng
Schlagworte:
AGARICUS
Agaricus - chemistry
Agaricus - growth & development
Agaricus blazei
Agaricus blazei Murill
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
ANTIVIRAL AGENTS
Antiviral Agents - isolation & purification
Antiviral Agents - pharmacology
Biological and medical sciences
Cercopithecus aethiops
cytopathic effect
Cytopathogenic Effect, Viral - drug effects
Encephalitis Virus, Western Equine - drug effects
Encephalitis Virus, Western Equine - pathogenicity
EQUINE ENCEPHALOMYELITIS VIRUS
IN VITRO EXPERIMENTATION
INHIBITION
Medical sciences
Pharmacology. Drug treatments
VERO cells
western equine encephalitis (WEE) virus
Western equine encephalitis virus
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Zusammenfassung:Antiviral activities of Agaricus blazei Murill were investigated. The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol. To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethanol fractions was tested. Strong inhibition of CPE induced by western equine encephalitis (WEE) virus was observed in the mycelial fractions but not those of fruiting bodies. ---[End of Page 9]---
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.65.1645