Enzymatic preparation of genuine prosapogenin, 20(S)-ginsenoside Rh1, from ginsenosides Re and Rg1

It was found that a lactase preparation from Penicillium sp. nearly quantitatively hydrolyzed ginsenosides Re and Rg 1 , which are major saponins in roots of Panax ginseng, to a minor saponin, 20(S)-ginsenoside Rh 1 [6-O-β-D-glucopyranosyl-20(S)-protopanaxatriol]. This is the first report on the enz...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2000-12, Vol.64 (12), p.2739-2743
Hauptverfasser: Ko, S.R. (Korea Ginseng and Tobacco Research Inst., Taejon (Korea R.)), Suzuki, Y, Choi, K.J, Kim, Y.H
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Sprache:eng
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Zusammenfassung:It was found that a lactase preparation from Penicillium sp. nearly quantitatively hydrolyzed ginsenosides Re and Rg 1 , which are major saponins in roots of Panax ginseng, to a minor saponin, 20(S)-ginsenoside Rh 1 [6-O-β-D-glucopyranosyl-20(S)-protopanaxatriol]. This is the first report on the enzymatic preparation of ginsenoside Rh 1 with a high efficiency. This enzyme also readily hydrolyzed ginsenoside Rg 2 to ginsenoside Rh 1 .
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.64.2739