Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull

Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorg...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1998-11, Vol.62 (11), p.2273-2276
Hauptverfasser:	Cho, J.Y. (Chonnam National Univ., Kwangju (Korea R.)), Moon, J.H, Seong, K.Y, Park, K.H
Format:	Artikel
Sprache:	eng
Schlagworte:	4-hydroxybenzoic acid ACIDE BENZOIQUE ACIDE CINNAMIQUE ACIDO BENZOICO ACIDOS CINAMICOS Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology antimicrobial activity ANTIMICROBIALS ANTIMICROBIANOS ANTIMICROBIEN BACTERIA Bacterial plant pathogens BALLE DE RIZ BENZOIC ACID Biological and medical sciences Biological Assay CASCARILLA DE ARROZ Cereal and baking product industries CINNAMIC ACIDS Coumaric Acids - isolation & purification Coumaric Acids - pharmacology ESPECTROMETRIA DE MASAS Food industries Fundamental and applied biological sciences. Psychology Generalities. Techniques. Transmission, epidemiology, ecology. Antibacterial substances, control Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects GROWTH INHIBITORS HPLC IDENTIFICACION IDENTIFICATION INHIBIDORES DEL CRECIMIENTO INHIBITEUR DE CROISSANCE MASS SPECTROMETRY Molecular Weight Oryza - chemistry Parabens - isolation & purification Parabens - pharmacology Phytopathology. Animal pests. Plant and forest protection Propionates rice hull RICE HUSKS SEPARACION SEPARATING SEPARATION SPECTROMETRIE DE MASSE Stereoisomerism trans 4-hydroxycinnamic acid
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Zusammenfassung:	Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms. Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 mu-g/ml, respecti
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.62.2273