Total Synthesis of (+)-Phrymarolin I from (+)-Malic Acid

(+)-Phrymarolin I was stereoselectively synthesized from (R)-(+)-3-hydroxybutanolide that had been prepared from (+)-malic acid. The procedure is more efficient than our previous synthesis in terms of fewer reaction steps and the easier availability of the starting material.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1997, Vol.61 (4), p.660-663
Hauptverfasser:	Okazaki, Momotoshi, Ishibashi, Fumito, Shuto, Yoshihiro, Taniguchi, Eiji
Format:	Artikel
Sprache:	eng
Schlagworte:	(+)-phrymarolin I (R)-(+)-3-hydroxybutanolide Chemistry Exact sciences and technology furofuran lignan Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Organic chemistry Preparations and properties stereoselective synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	(+)-Phrymarolin I was stereoselectively synthesized from (R)-(+)-3-hydroxybutanolide that had been prepared from (+)-malic acid. The procedure is more efficient than our previous synthesis in terms of fewer reaction steps and the easier availability of the starting material.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.61.660