Apoptosis to HL-60 by Humulone
Humulone, a bone resorption inhibitor isolated from hop extract, induced apoptosis in the premyocytic leukemia cell line HL-60 between 1 and 100 μg/ml. Our data suggested that there was a correlation between the apoptosis-inducing activity of humulone and its antioxidative activity.
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1997, Vol.61 (6), p.1027-1029 |
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| container_end_page | 1029 |
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| container_issue | 6 |
| container_start_page | 1027 |
| container_title | Bioscience, biotechnology, and biochemistry |
| container_volume | 61 |
| creator | Tobe, Hiroyasu Kubota, Mitsuaki Yamaguchi, Mitsune Kocha, Tomoji Aoyagi, Takaaki |
| description | Humulone, a bone resorption inhibitor isolated from hop extract, induced apoptosis in the premyocytic leukemia cell line HL-60 between 1 and 100 μg/ml. Our data suggested that there was a correlation between the apoptosis-inducing activity of humulone and its antioxidative activity. |
| doi_str_mv | 10.1271/bbb.61.1027 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0916-8451 |
| ispartof | Bioscience, biotechnology, and biochemistry, 1997, Vol.61 (6), p.1027-1029 |
| issn | 0916-8451 1347-6947 |
| language | eng |
| recordid | cdi_proquest_journals_1449425219 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Open Access Titles of Japan; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | Anti-Infective Agents - pharmacology Anticarcinogenic Agents - toxicity antioxidant Antioxidants - pharmacology apoptosis Apoptosis - drug effects Apoptosis - genetics Ascorbic Acid - pharmacology Biological and medical sciences Bone Resorption - prevention & control bone resorption inhibitor Cell Division - drug effects Cyclohexenes DNA Fragmentation - drug effects Dose-Response Relationship, Drug General pharmacology Genistein HL-60 HL-60 Cells - cytology HL-60 Cells - drug effects Humans humulone Isoflavones - pharmacology Lethal Dose 50 Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Quercetin - pharmacology Terpenes - pharmacology Tumor Cells, Cultured |
| title | Apoptosis to HL-60 by Humulone |
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