Isolation and identification of antimicrobial compounds in Brazilian propolis

Three distinct antimicrobial compounds were isolated from Brazilian propolis. These compounds were identified as 3,5-diprenyl-4-hydroxycinnamic acid (1), 3-prenyl-4-dihydrocinnamoloxycinnamic acid (2), and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzopyran (3). The respective antimicrobial activity, expr...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1994, Vol.58 (5), p.945-946
Hauptverfasser:	Aga, H. (Hayashibara Biochemical Labs. Inc., Okayama (Japan)), Shibuya, T, Sugimoto, T, Kurimoto, M, Nakajima, S
Format:	Artikel
Sprache:	eng
Schlagworte:	ABEILLE DOMESTIQUE ABEJA MELIFERA ANTIMICROBIANO ANTIMICROBIEN Biological and medical sciences BRASIL BRESIL General pharmacology IDENTIFICACION IDENTIFICATION Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PROPOLEOS PROPOLIS
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Zusammenfassung:	Three distinct antimicrobial compounds were isolated from Brazilian propolis. These compounds were identified as 3,5-diprenyl-4-hydroxycinnamic acid (1), 3-prenyl-4-dihydrocinnamoloxycinnamic acid (2), and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzopyran (3). The respective antimicrobial activity, expressed as MIC in mu-g/ml, 1-3 against Bacillus cereus was 15.6, 31.3, and 125; that against Enterobacter aerogenes was 31.3, 62.5, and 125; and that against Arthroderma benhamiae was 15.6, 250, and 62.5. Compound 1 is likely to be one of the major antimicrobial compounds in Brazilian propolis
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.58.945