Identification and Characterization of Antioxidants from Sophora flavescens

The objectives of this study were to investigate the radical-scavenging activity and protective potential of Sophora flavescens from oxidative damage by the radical generator 2,2′-azobis(2-amidinopropane)dihydrochloride (AAPH) in renal epithelial LLC-PK1 cells and to identify the active components u...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & pharmaceutical bulletin 2006, Vol.29(9), pp.1911-1915
Hauptverfasser:	Piao, Xiang-Lan, Piao, Xiang Shu, Kim, Sung Woo, Park, Jeong Hill, Kim, Hyun Young, Cai, Shao-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidines - toxicity Animals Antioxidants - analysis Antioxidants - pharmacology antioxidative activity Chromatography, High Pressure Liquid Flavanones - pharmacology Flavonoids - pharmacology HPLC/MS kurarinone LLC-PK1 Cells Magnetic Resonance Spectroscopy Mass Spectrometry Plant Extracts - pharmacology Sophora - chemistry Sophora flavescens sophoraflavanone G
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The objectives of this study were to investigate the radical-scavenging activity and protective potential of Sophora flavescens from oxidative damage by the radical generator 2,2′-azobis(2-amidinopropane)dihydrochloride (AAPH) in renal epithelial LLC-PK1 cells and to identify the active components using the bioassay-linked fractionation method. The MeOH extract and fractions of CH2Cl2, BuOH, and H2O from S. flavescens showed 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging effects in a dose-dependent manner (p
ISSN:	0918-6158 1347-5215
DOI:	10.1248/bpb.29.1911